From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Targeted and streamlined operation with MGI ATOPLEX technology

Fast image

Full rapid process and reporting

Suitable for culture-free sample

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Targeted and streamlined operation with MGI ATOPLEX technology

Fast image

Full rapid process and reporting

Suitable for culture-free sample

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Targeted and streamlined operation with MGI ATOPLEX technology

Fast image

Full rapid process and reporting

Suitable for culture-free sample

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Targeted and streamlined operation with MGI ATOPLEX technology

Fast image

Full rapid process and reporting

Suitable for culture-free sample

Comprehensive software analysis

Revolutionize Your Mycobacterium Tuberculosis Research with MGI's Cutting-Edge ATOPLEX & MTB-Explorer Software

Next Generation Sequencing has provided insights into the genetic diversity of Mycobacterium Tuberculosis, which are crucial for understanding the evolution and transmission of the disease, including the identification of drug-resistant strains, enabling rapid and accurate tailoring of treatment.

MGI has developed an ATOPlex Mycobacterium Tuberculosis targeted sequencing sample to report workflow, providing full and complete MTB identification and drug resistance analysis. Based on MGI’s ATOPlex multiplex PCR library preparation platform, 2-step amplification in one tube is needed to achieve target area amplification and library construction, supporting direct detection of nucleic acid extracted from sputum and lavage fluid samples.

Combined with MGI’s MTB-Explorer Software, provides identification of 174 types of mycobacteria, MTBC identification, spoligotyping, and evolutionary traceability analysis. Specifically for drug resistance, the software covers a total of 7000+ mutations, including all of the 1200+ first-and second-group drug resistance associated mutations associated with the “Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance" released by WHO for annotation.

MGI's ATOPlex Mycobacterium Tuberculosis targeted sequencing workflow
Sample to report in as fast as 24h

Library Preparation

7~8h

ATOPlex MTB Library Preperation Set

DNBSEQ OneStep Make DNB Reagent Kit V4.0 (Dua Barcode)
MGISP-100 Automation Machine from MGI-Tech

Sequencing

~12-20h

High-throughput Sequencing Set
DNBSEQ-G99 SM FCL PE150 12h
DNBSEQ-E25 FCL PE150 20h
DNBSEQ-G99 FLOW CELL

Analysis

2-6h

MTB-Explorer Software

Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)

MTB-Explorer Software (ATOPLex)

V1.0.0
Summary

Data
Quality control
Clean data
MTBC species
reference
Species identification
Negative/Positive
judgement
Negative
report
Positive
M.tuberculosis
reference
(H37Rv)
Alignment
Lineage &
Spoligotype
Lineage &
Spoligotype
results
Variant Calling
Consensus
sequence
Evolutionary analysis (Tree)
Evolutionary analysis (Tree)
Annotation
MTB drug resistance database
Drug Resistance
Prediction results

Mycobacterium Tuberculosis Next Generation Sequencing DNBSEQ-G99/E25

A powerful tool for Mycobacterium Tuberculosis analysis

Library Preparation

Sequencing

Data Analysis

ATOPlex MTB Library Preparation Set

Designed specifically for MTBC identification and MTB drug resistance gene detection

DNBSEQ OneStep Make DNB Reagent Kit V4.0 (Dual Barcode)

Simplified sequencing process: Direct access to DNB samples.

TB Reagent Kits and Flowcell

Mycobacterium Tuberculosis Next Generation Sequencing DNBSEQ-G99/E25

A powerful tool for Mycobacterium Tuberculosis analysis

Library Preparation

Sequencing

Data Analysis

ATOPlex MTB Library Preparation Set

Designed specifically for MTBC identification and MTB drug resistance gene detection

DNBSEQ OneStep Make DNB Reagent Kit V4.0 (Dual Barcode)

Simplified sequencing process: Direct access to DNB samples.

TB Reagent Kits and Flowcell

Mycobacterium Tuberculosis Next Generation Sequencing DNBSEQ-G99/E25

A powerful tool for Mycobacterium Tuberculosis analysis

Library Preparation

Sequencing

Data Analysis

ATOPlex MTB Library Preparation Set

Designed specifically for MTBC identification and MTB drug resistance gene detection

DNBSEQ OneStep Make DNB Reagent Kit V4.0 (Dual Barcode)

Simplified sequencing process: Direct access to DNB samples.

TB Reagent Kits and Flowcell

Precision and Performance With The DNBSEQ-G99 & DNBSEQ-E25

DNBSEQ-G99

DNBSEQ-E25

Samples per run icon
Samples per run

≤4-8 sample /FC

MGI Flow cells icon
Flow Cells

1

Read Lengths

FCL PE150

Nucleic Acid to report

28.5

DNBSEQ-G99

DNBSEQ-E25

Samples per run icon
Samples per run

≤24 samples /FC

MGI Flow cells icon
Flow Cells

2

Read Lengths

FCL PE150

Nucleic Acid to report

24h

DNBSEQ-G99

DNBSEQ-E25

Samples per run icon
Samples per run

≤4-8 sample /FC

MGI Flow cells icon
Flow Cells

1

Read Lengths

FCL PE150

Nucleic Acid to report

28.5

Certification

ISO 13485

Medical Device Quality Management System

ISO 14001

Environmental Management System

ISO 27001

Information Security Management System

Certification

ISO 13485

Medical Device Quality Management System

ISO 14001

Environmental Management System

ISO 27001

Information Security Management System

Certification

ISO 13485

Medical Device Quality Management System

ISO 14001

Environmental Management System

ISO 27001

Information Security Management System

Certification

ISO 13485

Medical Device Quality Management System

ISO 14001

Environmental Management System

ISO 27001

Information Security Management System

Resources

Brochure & Manuals

Resources

Brochure & Manuals

Resources

Brochure & Manuals

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*For Research Use Only

Not for use in diagnostic procedures (except as specifically noted).

Copyright © 2024 MGI tech GmbH, Ltd. All Rights Reserved.

Join our newsletter to stay up to date on features and releases.

I have read and understood MGI’s Privacy Policy, and I consent to the collection and processing of my personal data for handling, responding to my contact, receiving your newsletter as well as promotion and marketing activities.

*For Research Use Only

Not for use in diagnostic procedures (except as specifically noted).

Copyright © 2024 MGI tech GmbH, Ltd. All Rights Reserved.

Join our newsletter to stay up to date on features and releases.

I have read and understood MGI’s Privacy Policy, and I consent to the collection and processing of my personal data for handling, responding to my contact, receiving your newsletter as well as promotion and marketing activities.

*For Research Use Only

Not for use in diagnostic procedures (except as specifically noted).

Copyright © 2024 MGI tech GmbH, Ltd. All Rights Reserved.